pleiotropic mutation meaning in Chinese

多效突变：使不同性状发生改变的突变。

S . lividans mutant strains zx1 ( dnd cluster deleted ) and zx64 ( dnda disrupted ) had pleiotropic mutations including low mel expression and poor sporulation . it was speculated that dnda together with its downstream dna ( 2 . 5kb ) might be involved in these two phenotypes because dnda together with its downstream dna could restore normal sporulation and mel expression to zx64 , while dndb and dndc had no such effect because lai and la2 showed no obvious difference in these two phenotypes from wild type s . lividans 1326
另外通过比较这几个突变株及野生型菌株在产孢和黑色素基因( mel )表达方面的差异，推测dnda及其下游区域与变铅青链霉菌的产孢和刺激外源黑色素基因的表达有关，而dndb和dndc则与之无关，因为la1和la2在这两种表型上与野生型菌株无明显差异。